This new therapy for equine joint disease slows the progression of osteoarthritis by inhibiting factors that lead to cartilage breakdown. A2M is a molecule that is found naturally in the blood and has been found to help prevent cartilage breakdown. Due to its large size and structure however, it is unable to reach high concentrations in joint spaces. Blood is drawn from the patient and specially filtered to concentrate the A2M molecule. The product can then be injected into effected joints to help decrease inflammation, relieve pain, and protect the joint by preventing cartilage breakdown. The remaining concentrated A2M product may be frozen and used for future injections.

What is Alpha 2EQ?
Alpha 2EQ is a system that isolates and concentrates the Alpha 2 Macroglobulin (α2M) molecule from a horse’s blood.

How does Alpha 2EQ Work?
Alpha 2 Macroglobulin (α2M) inhibits all 4 classes of proteases, including the enzymes that breakdown joint cartilage. It inhibits these enzymes using a “trapping mechanism,” similar to the way a Venus fly trap captures its prey.

How is Alpha 2EQ Administered?
Alpha 2EQ can be administered by your veterinarian directly into joints (intra-articular) or in and around soft tissue, such as flexor tendons or suspensory ligaments.

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